MT-ND4 pseudogene 28 (MTND4P28)

MT-ND4 pseudogene 28 (MTND4P28) is a nuclear-encoded, non-coding pseudogene derived from mitochondrial DNA, specifically related to the genuine MT-ND4 gene, which encodes a subunit of mitochondrial complex I (NADH:ubiquinone oxidoreductase). Unlike protein-coding genes, pseudogenes such as MTND4P28 do not produce functional proteins and do not contribute to mitochondrial electron transport or ATP synthesis. Pseudogenes typically arise from the integration of mitochondrial DNA fragments into the nuclear genome and are non-functional due to accumulated mutations, including premature stop codons. There is no evidence that MTND4P28 acts as a functional therapeutic target, participates in biological processes, is involved in disease, interacts with drugs, or serves as a biomarker. As a pseudogene, it is not considered a therapeutic target and lacks biological or pharmacological relevance as a target or biomarker. The term "MT-ND4 pseudogene 28" is not found in canonical gene databases as a functional target, receptor, enzyme, transporter, or biomarker, and its name may reflect confusion with the functional mitochondrial MT-ND4 gene.

Other names

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 pseudogene 28MTND4P28