MT-ND4 pseudogene 31 (MTND4P31)

MT-ND4 pseudogene 31 (MTND4P31) is a pseudogene; it is a genomic DNA segment with sequence similarity to the functional MT-ND4 gene but does not produce a functional protein. Pseudogenes generally arise through gene duplication or retrotransposition events followed by the accumulation of disabling mutations. MTND4P31 is annotated as a non-functional copy and does not have established roles in biological function, disease, or as a therapeutic target[7].\n\nThis entry is not considered a therapeutic target such as a receptor, enzyme, transporter, or transcription factor. There is no evidence in the literature or genetic databases for MTND4P31 being involved in disease, response to drugs, or other molecular functions—it is simply considered a nonfunctional sequence related to the mitochondrial ND4 gene[7].\n\nIf you are seeking information about the functional, protein-coding mitochondrial gene, refer to \"NADH-ubiquinone oxidoreductase chain 4\" (abbreviated as MT-ND4 or ND4), which is an integral component of mitochondrial complex I, involved in electron transport and energy production, and implicated in diseases such as Leber hereditary optic neuropathy[1][2][3][4][5]. However, \"MT-ND4 pseudogene 31\" is not equivalent to MT-ND4, and does not share those biological or therapeutic significances[7].

Other names

MTND4P31MT-ND4P31