MT-ND5 pseudogene 2 (MTND5P2)

**MT-ND5 pseudogene 2 (MTND5P2)** is a nuclear pseudogene corresponding to the mitochondrial NADH:ubiquinone oxidoreductase core subunit 5 gene (ND5)[6][8]. Unlike the functional mitochondrial ND5 gene, MTND5P2 is a non-coding sequence embedded in the nuclear genome and does not encode a functional protein. MTND5P2 is classified as a pseudogene that likely arose from nuclear integration of mitochondrial DNA (NUMT) and harbors mutations and truncations that prevent translation into a functional protein[6][7][8]. There is no evidence in the scientific literature that MTND5P2 plays a direct role in biological pathways, disease, or drug targeting. **Summary of findings:** - MT-ND5 pseudogene 2 is a **pseudogene** and not a conventional drug target or functional protein[6][8]. - It does **not encode an enzyme, receptor, or transporter**, and there is no evidence for its role in signaling or cellular function[6][7][8]. - No drugs, biomarkers, or disease roles are directly associated with this gene. Please note that this distinguishes MTND5P2 from the functional mitochondrial gene MT-ND5, which is involved in mitochondrial respiratory complex I and is important in energy production and disease[1][3][7].

Other names

MTND5P2mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 pseudogene 2MT-ND5P2NADH dehydrogenase 5 pseudogene 2