MT-ND5 pseudogene 6 (MTND5P6)

MT-ND5 pseudogene 6 (MTND5P6) is a nuclear pseudogene related to the mitochondrial gene MT-ND5, which codes for a subunit of NADH dehydrogenase in the mitochondrial respiratory chain[8][6]. As a pseudogene, MTND5P6 does not encode a functional protein and has no known biological activity or disease association. Its presence can complicate genetic analyses involving the functional MT-ND5 gene by leading to non-specific amplification or erroneous interpretation of variants, but it is not itself a therapeutic target or involved in disease mechanisms[5][8][6]. If information about the functional mitochondrial gene "MT-ND5" is required, it has documented roles in the mitochondrial electron transport chain and is associated with various mitochondrial diseases[1][2][3]. However, MTND5P6 specifically refers to a pseudogene and not to a functional target.

Other names

MTND5P6Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 pseudogene 6

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