MT-ND6 pseudogene 17 (MTND6P17)

MT-ND6 pseudogene 17 (MTND6P17) is a nuclear-encoded sequence annotated as a pseudogene related to the mitochondrial gene MT-ND6 (NADH:ubiquinone oxidoreductase core subunit 6). Unlike the true mitochondrial MT-ND6 gene—which encodes a protein subunit of mitochondrial Complex I and is implicated in diseases such as Leber hereditary optic neuropathy and Leigh syndrome—this pseudogene does not produce a functional protein. Pseudogenes generally result from duplication or reverse transcription events and typically lack the regulatory and coding sequences necessary for gene expression. There is no evidence that MTND6P17 is functionally transcribed or translated, nor does it play a direct role in biological pathways, disease, or as a therapeutic target[1][2][3][4].\n\nIf you require information about the functional and disease relevance of the bona fide mitochondrial gene MT-ND6, let me know.

Other names

MT-ND6 pseudogene 17MTND6P17MTND6 pseudogene 17, mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 pseudogene 17