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Target intelligence / Profile preview
MT-RNR2-like 6 (MTRNR2L6)
- Target
- MTRNR2L6
- Molecular classification
- Other (Pseudogene), Predicted protein may have receptor antagonist activity
01
Overview
MT-RNR2-like 6 (MTRNR2L6) is a gene in humans, annotated as a pseudogene on chromosome 7. It is part of the family of nuclear genes that are similar to MT-RNR2, a mitochondrial gene encoding the Humanin peptide. Humanin-like 6 is predicted to have receptor antagonist activity and may play a neuroprotective or antiapoptotic role, though direct evidence of expression and function in humans is lacking. MTRNR2L6 is not recognized as a classical therapeutic target (receptor, enzyme, transporter, etc.) due to its pseudogene status and uncertain biological activity[2][4][7][8].
- Other names
- MTRNR2L6HN6MT-RNR2 like 6Humanin-like 6MT-RNR2-like 6 (pseudogene)
02
Biological functions
Neuroprotection (predicted/putative)antiapoptotic factornegative regulation of execution phase of apoptosis (predicted)
03
Disease associations
None established; some associations with Hordeolum externum and internal hordeolum are reported but not well-supported
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