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Mucopolysaccharides (GAG)
- Target
- GAG
- Molecular classification
- Polysaccharide, Biopolymer
01
Overview
Mucopolysaccharides, also known as glycosaminoglycans (GAGs), are long, unbranched polysaccharide chains composed of repeating disaccharide units. They are found throughout the body and play crucial roles in building bone, cartilage, tendons, corneas, skin, and connective tissue. Deficiency in lysosomal enzymes required for GAG degradation leads to mucopolysaccharidoses, a group of lysosomal storage disorders characterized by GAG accumulation and progressive cellular damage.
- Other names
- Glycosaminoglycans
02
Mechanism of action
N/A
03
Biological functions
Structural support in connective tissueMaintain viscosity and elasticity of extracellular matrixComponent of mucusComponent of joint fluid
04
Disease associations
Mucopolysaccharidoses (MPS)
05
Safety considerations
Accumulation due to enzyme deficiency leads to cellular damage
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