Mucosal Immunity Induction via Intranasal Administration (Intranasal Mucosal Immunity)

Induction of mucosal immunity via intranasal administration is a vaccination strategy that delivers antigens through the nasal route to stimulate immune responses at mucosal surfaces, particularly in the respiratory tract. This approach aims to generate both local (mucosal) and systemic immunity, providing protection at the primary entry point for many pathogens. It relies on the activation of NALT, production of secretory IgA, and induction of tissue-resident memory cells.

Other names

Intranasal VaccinationNasal Vaccine DeliveryMucosal Vaccine AdministrationNALT-targeted Immunity

Antigen presentation in NALT, activation of B and T cells, production of secretory IgA, induction of tissue-resident memory cells.