Mugwort pollen allergen (Art v (component name, e.g., Art v 1, Art v 3))

Mugwort pollen allergens are a complex mixture of proteins derived from the pollen of **Artemisia vulgaris** (mugwort), a weed from the family *Asteraceae* (Compositae)[1][3]. The major clinically relevant molecules are **Art v 1** (defensin-like protein) and **Art v 3** (non-specific lipid transfer protein), among others (Art v 2, Art v 4, Art v 5, Art v 6)[1][2]. These proteins are recognized by IgE antibodies in genetically predisposed individuals and trigger type I hypersensitivity reactions, causing symptoms such as allergic rhinitis, conjunctivitis, asthma, and sometimes systemic reactions (pollen allergy and pollen-food allergy syndrome)[1][2][3]. Pollen-derived allergens exhibit extensive cross-reactivity with other members of the *Asteraceae* family (e.g., ragweed), and can cause food allergies due to structurally similar allergens in foods (e.g. celery, peach, mustard)[1][2]. The dominant protein responsible for respiratory symptoms is Art v 1, while Art v 3 is significant for cross-reactive food allergy syndromes[1][2]. Mugwort pollen is not a single therapeutic target, but a source of multiple functionally unrelated protein allergens, and "allergens from mugwort pollen" is a category, not a molecule.

Other names

Artemisia vulgaris pollen allergenmugwort pollenArt v allergenscommon wormwood allergenwild wormwood allergenfelon herb pollen allergen

Drugs used for allergy block IgE binding to allergens, dampen allergic inflammation, or desensitize the immune system to allergens (immunotherapy)