Multiple cardiovascular and inflammatory pathway proteins

The term "Multiple cardiovascular and inflammatory pathway proteins" refers to a heterogeneous collection of proteins rather than a single therapeutic target. This classification typically encompasses a wide array of cytokines, chemokines, growth factors, and enzymes that mediate the physiological and pathological processes linking systemic inflammation with cardiovascular health. These proteins are often studied collectively using high-throughput proteomic technologies, such as Olink proximity extension assays, to identify biomarkers for diseases like atherosclerosis, heart failure, and myocardial infarction (Lind et al., 2020, JAHA). Because this term represents a broad functional category involving hundreds of distinct molecular entities, it cannot be targeted by a single drug or mechanism. Instead, it serves as a framework for multi-omic research and the development of precision medicine strategies to monitor the pleiotropic effects of treatments on the cardiovascular-inflammatory axis (Heerspink et al., 2019, Circulation).

Other names

Cardiovascular and inflammatory biomarkersCV/Inflammation proteomic panelsInflammatory signaling proteins

Not applicable for a multi-protein group; however, drugs affecting these pathways often act through systemic metabolic, anti-inflammatory, or hemodynamic mechanisms.