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Target intelligence / Profile preview
Multiple Cardiovascular Targets via Multi-Component Herbal Action
- Molecular classification
- Multi-target therapy, Phytochemical mixtures, Herbal medicine
01
Overview
The "multiple cardiovascular targets via multi-component herbal action" refers not to one molecule/receptor but rather the simultaneous modulation of several key biological processes relevant to cardiovascular health through the combined action of diverse plant-derived compounds within traditional or modern polyherbal formulations. These formulations aim to address CVD by targeting multiple pathways such as inflammation, oxidative stress, endothelial dysfunction, and lipid metabolism, offering a holistic approach compared to single-target drugs.
- Other names
- Multi-component herbal preparations for cardiovascular diseasePolyherbal cardiovascular therapiesTraditional Chinese Medicine (TCM) for heart health
02
Mechanism of action
Multiple mechanisms including NF-kB inhibition, NO production enhancement, PI3K/Akt activation, lipid metabolism modulation, and ion channel modulation.
03
Biological functions
Anti-inflammationAntioxidationVasodilationAnti-thrombosisLipid metabolism regulationCardiac rhythm stabilization
04
Disease associations
HypertensionAtherosclerosisArrhythmiasHeart failureMyocardial infarctionCoronary artery diseaseDyslipidemia
05
Safety considerations
Herb-drug interactionsVariability in product qualityLack of standardizationPotential adverse effects of individual herbs
06
Interacting drugs
Warfarin
3 more in the full profile.
07
Biomarkers
Blood pressureLipid profile (LDL, HDL, triglycerides)Inflammatory markers (e.g., CRP, IL-6)Endothelial function markers (e.g., flow-mediated dilation)
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