Multiple cytokines

Cytokines are a large, diverse family of secreted signaling proteins and glycoproteins released primarily by immune cells to mediate intercellular communication, regulate immunity, inflammation, hematopoiesis, tissue repair, and homeostasis. They act through high-affinity cell surface receptors, initiating intracellular signaling cascades such as JAK/STAT and NF-κB to modulate gene expression and cellular responses. Dysregulation of cytokine networks is linked to a range of diseases including inflammation, cancer, infection, and autoimmune disorders. Because "multiple cytokines" refers collectively to this entire class, it is not a precise drug target; rather, individual cytokines (like interleukin-6, tumor necrosis factor alpha, or interferon gamma) are specific and actionable molecular targets in research and therapy.

Other names

CytokinesImmune cytokinesSignaling cytokinesInflammatory cytokinesSoluble mediators

Inhibition of cytokine production or signaling (e.g., JAK/STAT inhibitors, anti-cytokine antibodies); Cytokine receptor blockade; Immunomodulation via regulation of cytokine expression or release