Multiple immune and inflammatory targets

The label "Multiple immune and inflammatory targets" describes an aggregate of molecular entities, including receptors (e.g., TNF receptors, interleukin receptors), enzymes (e.g., Janus kinases), cytokines, chemokines, and other signaling proteins that collectively mediate and regulate immune and inflammatory responses. These targets are not a single molecule but a large set of potential drug targets prioritized for their relevance in immune-mediated and inflammatory diseases. Databases and resources (such as the Priority index, Guide to Immunopharmacology, and Olink’s Target 48 panel) organize and prioritize these targets based on evidence from genetics, protein interactions, and therapeutic tractability, enabling drug discovery efforts to focus on the most relevant molecular nodes within complex immune pathways[1][2][5][8]. This entry should not be used as a canonical target and is too broad for direct annotation in a structured target database. For specific molecular target annotation, refer to the individual gene/protein names within immune and inflammatory pathways (e.g., "Interleukin-6 receptor," "Tumor necrosis factor receptor," "Janus kinase 1").

Other names

Multiple immune targetsMultiple inflammatory targetsImmune-related targetsInflammatory mediators