Target intelligence / Profile preview

Multiple Inflammatory Cytokines

Molecular classification
Secreted protein, Signaling molecule, Cytokine
01

Overview

Multiple inflammatory cytokines are a group of secreted proteins that act as key signaling molecules in the immune system, mediating and regulating inflammation. These cytokines are produced by various cell types in response to infection, injury, or other immune challenges. They function as chemical messengers that coordinate the body's response to threats by activating immune cells and orchestrating both local and systemic inflammatory responses. Key members include IL-1α/β, IL-6, TNF-α, IL-12, IL-18, and IFNγ. Dysregulation can lead to numerous diseases, including autoimmune disorders, chronic inflammatory diseases, and cancer.

Other names
Pro-inflammatory CytokinesInflammatory MediatorsCytokine storm mediators
02

Biological functions

Immune responseInflammationCell signalingRecruitment of immune cellsInduction of acute-phase proteinsT helper cell differentiationFever inductionPain sensitization
03

Disease associations

Autoimmune disordersChronic inflammatory diseasesAtherosclerosisCancerNeurological conditionsDepressionInfection
04

Safety considerations

Excessive inflammationTissue damageCytokine stormImmunosuppression

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