Multiple neurotransmitter systems

"Multiple neurotransmitter systems" is not the name of a single molecule or receptor but refers collectively to several distinct chemical signaling pathways in the nervous system. Each "system" is defined by its primary signaling molecule—such as acetylcholine for cholinergic neurons; dopamine for dopaminergic neurons; serotonin for serotonergic neurons; glutamate and GABA for glutamatergic and GABAergic neurons respectively—and includes all relevant synthetic enzymes, transporters, vesicular packaging proteins, release mechanisms at synapses, postsynaptic receptors (which may be ion channels or G protein-coupled receptors), and reuptake/degradation machinery[2][4][5]. These various transmitter systems regulate nearly every aspect of brain function including movement control (dopamine), mood regulation (serotonin), learning/memory (acetylcholine/glutamate), inhibition/excitation balance (GABA/glutamate), among others[1][3]. Dysregulation across one or more transmitter systems underlies many neurological and psychiatric diseases. However, "multiple neurotransmitter systems" does not refer to any one therapeutic target but rather an entire class comprising many different molecular entities—each with its own structure-function relationships and pharmacology. **Note:** The entry "Multiple neurotransmitter systems" is too broad/vague for structured data about an individual drug target. It should be replaced by specific names such as "Dopamine D2 receptor," "Serotonin transporter," etc.[2]

Other names

Multiple neurotransmitter systemsNeurotransmitter systemsNeurotransmitters (when used in a broad/systemic sense)