Multiple protein targets and pathways

The term Multiple protein targets and pathways does not refer to a specific biological molecule, receptor, or enzyme, but rather describes a pharmacological strategy or a broad category of therapeutic action. In the context of drug discovery, this designation is often associated with polypharmacology, where a single therapeutic agent or a combination of drugs is designed to modulate several distinct proteins or signaling pathways simultaneously (Hopkins, 2008, Nature Chemical Biology). This approach is particularly relevant in treating complex, multifactorial diseases such as cancer or neurodegenerative disorders, where targeting a single node in a biological network may be insufficient due to compensatory mechanisms or redundancy (Anighoro et al., 2014, Journal of Medicinal Chemistry). Because this entry represents a collection of targets rather than a single entity, it lacks a unique molecular classification, specific biological function, or standardized identifier like a UniProt accession number. Consequently, it is considered an incorrect or overly broad entry for structured target-specific databases.

Other names

PolypharmacologyMulti-target therapyNetwork pharmacologyMulti-target drugs

Not applicable as this is a collective term for multiple distinct mechanisms.