Multiple proteins and pathways

"Multiple proteins and pathways" refers to the collective consideration of several protein targets and the biological pathways in which they are involved, rather than a single molecular entity. This terminology is commonly used in systems biology, polypharmacology, and network pharmacology to reflect approaches that target more than one protein or pathway simultaneously for therapeutic intervention[1][3][6]. Because it is not a precise molecular target, it cannot be mapped to the standard structured information expected for individual proteins, receptors, enzymes, or other molecular entities. As such, using "multiple proteins and pathways" as a target leads to missing or nonspecific information, and it does not comply with conventions for therapeutic target nomenclature or drug development databases[3][5][7]. **Note:** - This entry is too general, not a molecular target, and thus inappropriate for detailed target annotation or structured data extraction. - For structured data, it is essential to specify individual protein or pathway targets (e.g., "Janus kinase 1" or "STAT3") instead of a generic umbrella term.