Mycobacterial Energy Metabolism (N/A)

Mycobacterial energy metabolism encompasses the biochemical pathways and molecular machinery used by Mycobacterium species, including Mycobacterium tuberculosis, to generate, store, and utilize energy. Key pathways include the TCA cycle, glycolysis, pentose phosphate pathway, fatty acid metabolism, and the electron transport chain. The system is highly adaptable, allowing mycobacteria to survive under diverse environmental conditions such as nutrient limitation and hypoxia. Targeting mycobacterial energy metabolism, especially components like ATP synthase or specific ETC complexes, is an attractive strategy for novel anti-tubercular therapies.

Other names

Mycobacterium tuberculosis energy metabolismMtb energy metabolismMycobacterial bioenergeticsTuberculosis metabolism

Inhibition of ATP synthesis; Disruption of electron transport chain; Targeting metabolic enzymes