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Mycobacterium bovis cell wall biosynthesis pathway

Molecular classification: Biosynthetic pathway, Enzyme complex (for specific components, e.g., MurA, AftB, NAT), Transporter (for mycolic acid export, e.g., MmpL3)[6]

Overview

Other names: Mycobacterial cell wall biosynthesisMycobacterium tuberculosis cell wall biosynthesis (closely related)Mtb cell wall synthesis (commonly used in literature for both M. tuberculosis and M. bovis)Cell envelope biosynthesisMycolyl-arabinogalactan-peptidoglycan complex biosynthesis[1][2][7]

Biological functions

Cell growth and divisionMaintenance of cellular integrity and shapeVirulence factor productionImmune evasion[3][7]Masking pathogen-associated molecular patterns (PAMPs)Inhibition of innate immune responses such as autophagy and cytokine activation[3]Modulation of antigen presentation pathways[3]

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