Target intelligence / Profile preview

Mycobacterium tuberculosis (M. tuberculosis)

Target: M. tuberculosis
Molecular classification: Bacteria, Pathogen

Overview

Mycobacterium tuberculosis is the causative agent of tuberculosis (TB). It is a slow-growing bacterium with a unique waxy cell wall rich in mycolic acids. It primarily infects the lungs but can affect other organs. Infection occurs via inhalation of airborne droplets. Treatment involves antibiotics, but drug resistance is a major challenge.

Other names: Tubercle bacillusKoch’s bacillus

Mechanism of action

Antibiotics like isoniazid and ethambutol target cell wall synthesis and other mechanisms within M. tuberculosis to inhibit its growth and replication.

Biological functions

InfectionReplicationColonization

Disease associations

TuberculosisLatent TB infectionActive TB disease

Safety considerations

Drug resistanceTreatment failureAdverse drug reactions

Interacting drugs

Isoniazid

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Drug pipeline

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Drug candidates
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Development stage

Clinical trials

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Competitive landscape

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Programs
Modalities
Indications

Literature & evidence

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Patents

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Research & analysis

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Biology
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