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Mycobacterium tuberculosis 32 kDa Antigen (Mtb32)

Target: Mtb32
Molecular classification: Serine protease, Antigen

Overview

Mtb32 is an immunogenic protein antigen from Mycobacterium tuberculosis. It is a serine protease secreted during bacterial growth. It is highly conserved and stimulates strong T-cell responses, making it a key component of subunit vaccines for tuberculosis. It also has potential applications in TB diagnostics.

Other names: MTB32ARv0125

Mechanism of action

Not applicable as a direct drug target; used as a vaccine antigen to stimulate immune responses

Biological functions

Immune responseT-cell activation

Disease associations

InfectionTuberculosis

Safety considerations

Potential for off-target immune responsesVaccine-related adverse events

Biomarkers

T-cell proliferationIFN-γ secretion

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