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Mycobacterium tuberculosis Antigen Ag85B (None)

Target: None
Molecular classification: Enzyme, Mycolyltransferase, Fibronectin-binding protein, Antigen

Overview

Antigen 85B (Ag85B) is a major secreted protein of Mycobacterium tuberculosis (Mtb). It functions as a diacylglycerol acyltransferase/mycolyltransferase, crucial for cell wall biosynthesis. Ag85B is highly immunogenic, inducing strong T-cell proliferation and IFN-γ secretion. It is a target for vaccine development and is used in diagnostic assays.

Other names: FbpBFibronectin binding protein BExtracellular alpha-antigenDiacylglycerol acyltransferase/mycolyltransferase 85BMycolyl transferase 85B

Mechanism of action

N/A

Biological functions

Cell wall biosynthesisImmune evasionFibronectin bindingT-cell activationIFN-gamma production

Disease associations

TuberculosisInfection

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