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Target intelligence / Profile preview
Mycobacterium tuberculosis Antigen Rv2608 (Rv2608)
- Target
- Rv2608
- Molecular classification
- PPE proteins, Antigen
01
Overview
Rv2608 encodes the M. tuberculosis PPE41 protein—a member of the immunomodulatory PE/PPE family—recognized for its diagnostic value due to strong humoral immunogenicity. While not highly sensitive on its own as a biomarker, truncation or combination with other antigens enhances detection rates across diverse patient groups. Its stable genetic profile and capacity for inducing protective immunity make it an attractive candidate both for improved diagnostics and inclusion in multi-component vaccine strategies against TB.
- Other names
- PPE41
02
Biological functions
Immune modulationAntigen presentationB-cell activationTh1-type immune response induction
03
Disease associations
TuberculosisInfection
04
Biomarkers
Antibody levels against Rv2608 for TB diagnosis
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