Target intelligence / Profile preview

Mycobacterium tuberculosis Antigen TB10.4 (TB10.4)

Target: TB10.4
Molecular classification: ESAT-6-like protein, Antigen

Overview

TB10.4 is a secreted ESAT‑6-like protein from *Mycobacterium tuberculosis*, strongly recognized by host adaptive immunity through multiple epitopes presented on both class I and II MHC molecules. Its robust immunogenicity makes it valuable for diagnostics as well as subunit vaccine development. However, some evidence suggests it may act partly as a decoy antigen during natural infection.

Other names: EsxH

Biological functions

Immune responseT cell activationPathogenesis

Disease associations

InfectionTuberculosis

Safety considerations

Potential for immune evasion through altered antigen processing/presentation or decoy effects

Biomarkers

TB10.4-specific T cell responses (e.g., IFN-gamma production)

Beyond the preview

Go deeper on Mycobacterium tuberculosis Antigen TB10.4 (TB10.4).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Mycobacterium tuberculosis Antigen TB10.4 (TB10.4).

Explore the full profile