Target intelligence / Profile preview

Mycobacterium tuberculosis Antigens: Rv2608, Rv3619, Rv3620, and Rv1813 (None)

Target
None
Molecular classification
Protein, Antigen
01

Overview

Rv2608, Rv3619, Rv3620, and Rv1813 are proteins from *Mycobacterium tuberculosis* (Mtb) that have been identified as immunogenic components relevant for vaccine development. These antigens are often studied individually or as part of a fusion protein (notably ID93) to enhance immune responses against Mtb infection. Rv2608, Rv3619, and Rv3620 are expressed during active TB disease, while Rv1813 is expressed primarily during latent infection stages. ID93, a fusion protein of these antigens, is under clinical investigation as a TB vaccine candidate.

Other names
Rv2608Rv3619Rv3620Rv1813ID93 antigens
02

Mechanism of action

Stimulation of T cell-mediated immunity via antigen presentation.

03

Biological functions

Immune responseT cell activationAntigen presentation
04

Disease associations

InfectionTuberculosis

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