Mycoplasma hyopneumoniae

Mycoplasma hyopneumoniae is a small, wall-less, gram-negative bacterium and the primary causative agent of porcine enzootic pneumonia, a chronic, economically significant respiratory disease of pigs[1][3][5][6][7]. It specifically colonizes the ciliated epithelium of the swine respiratory tract, adhering via major surface adhesins such as P97 and P102[1]. The pathogen damages the mucociliary apparatus, impairs ciliary function, and induces both local inflammation and susceptibility to secondary infections[1][3][5]. It is classified as a prokaryotic microorganism, not as a canonical drug target such as a receptor, enzyme, or transporter. Control strategies include vaccination (which limits severity but does not prevent infection) and antimicrobial therapy, though complete eradication in commercial swine herds is rare[3][4][7]. **Note:** - This entry is marked **is_incorrect: true** because “Mycoplasma hyopneumoniae” is a whole organism (prokaryotic pathogen), not a canonical drug target molecule (e.g., protein, receptor, enzyme). Thus, it does not fit standard target molecule database schemas. - The information above is structured for clarity but does not denote a singular molecular target. Preferred targets would be molecular components of M. hyopneumoniae (such as the P97 adhesin) rather than the organism as a whole.

Other names

M. hyopneumoniae

Inhibition of bacterial protein synthesis (by antimicrobials such as macrolides and tetracyclines)[4]