Mycoplasma hyopneumoniae antigen (M. hyo antigen)

Mycoplasma hyopneumoniae is the primary causative agent of enzootic pneumonia, a chronic and highly contagious respiratory disease in swine that causes significant economic losses worldwide due to reduced growth rates and increased susceptibility to secondary infections (Source: Wikipedia, VetBact). The Mycoplasma hyopneumoniae antigen refers to the immunogenic components of the bacterium, such as the P97 adhesin and other surface proteins, which are used in vaccines and diagnostic assays (Source: PubMed PMID: 9043142). These antigens facilitate the attachment of the bacteria to the ciliated epithelium of the porcine respiratory tract, leading to ciliostasis and epithelial damage (Source: PubMed PMID: 16461024). Therapeutic intervention primarily involves vaccination with inactivated whole-cell preparations (bacterins) or recombinant subunits to stimulate a protective immune response that prevents colonization (Source: PMC6879653). While antibiotics like macrolides and fluoroquinolones are used for treatment, they target bacterial replication rather than the antigens themselves, making vaccination the cornerstone of long-term control (Source: Frontiers in Microbiology).

Other names

M. hyopneumoniaeEnzootic pneumonia antigenP97 adhesinP46 surface proteinP102 proteinP159 proteinMycoplasma hyopneumoniae bacterin

Induction of active immunity through the production of specific antibodies and activation of T-cells to prevent bacterial attachment to respiratory cilia.