Myeloid leukemia factor 2 pseudogene

The myeloid leukemia factor 2 pseudogene (LOC100419977, ENSG00000253942) is a non-protein-coding genomic locus that is homologous to the functional gene myeloid leukemia factor 2 (MLF2). As a pseudogene, it is not expected to produce a functional protein product nor act as a direct therapeutic target[1][7][8]. Like other processed pseudogenes, it may potentially participate in regulation of gene expression through RNA-related mechanisms, such as competing for microRNA binding or serving as a decoy, although no direct functional evidence is available for this specific pseudogene[2][5]. The parental gene MLF2 is involved in transcription regulation and is associated with leukemia, but the pseudogene itself does not have a confirmed disease association, nor does it interact with known drugs[1][4]. This entry should be considered as a genomic non-coding element rather than a druggable target or marker.

Other names

LOC100419977ENSG00000253942