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Target intelligence / Profile preview
MYL12A pseudogene 1 (MYL12AP1)
- Target
- MYL12AP1
- Molecular classification
- Other, Pseudogene (Processed pseudogene), Non-coding RNA
01
Overview
MYL12A pseudogene 1 (MYL12AP1) is a processed pseudogene with high sequence similarity to the MYL12A gene, which codes for myosin regulatory light chain 12A, a protein involved in smooth muscle and non-muscle cell contraction, actin cytoskeleton regulation, and cell division. Unlike the functional gene, the pseudogene does not produce a protein and is not directly involved in any biological pathways or diseases. Some pseudogenes can generate non-coding RNAs with a modulatory effect on gene expression, but there is no evidence that MYL12AP1 has such functions. Pseudogenes such as MYL12AP1 are generally considered non-functional genomic sequences and not therapeutic targets.
02
Mechanism of action
None (pseudogenes do not encode active proteins for pharmacological action)
03
Biological functions
OtherNo direct biological function as a protein. However, some pseudogenes, through non-coding RNAs, may modulate expression of other genes, including the parental gene, but for MYL12AP1, there is no direct evidence for a bona fide function
04
Disease associations
OtherNone established directly for MYL12AP1. Expression of some pseudogenes is altered in disease and may indirectly affect disease, but there is no evidence for MYL12AP1 being a biomarker or causative gene in any disease
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