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Target intelligence / Profile preview
Myo-inositol-1-phosphate synthase
- Molecular classification
- Enzyme
01
Overview
Myo-inositol-1-phosphate synthase is a key enzyme in the biosynthesis of myo-inositol, catalyzing the first and rate-limiting step of this pathway. It converts D-glucose 6-phosphate into 1L-myo-inositol 1-phosphate in a NAD+-dependent manner. This reaction is essential for the production of all inositol-containing compounds, which are critical for various cellular processes including cell growth, oxidative stress resistance, and synthesis of signaling molecules.
- Other names
- Ino-1ISYNA1Myo-inositol phosphate synthaseInositol-3-phosphate synthase 1
02
Mechanism of action
Catalyzes the conversion of D-glucose 6-phosphate to 1L-myo-inositol 1-phosphate.
03
Biological functions
Myo-inositol biosynthesisCell growthOxidative stress protectionPrecursor synthesis for phosphatidylinositol lipids and signaling molecules
04
Disease associations
Oxidative stress related diseasesMetabolic disorders (impaired inositol metabolism)
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