Target intelligence / Profile preview

Myocardial Cell Membrane (Sarcolemma)

Target: Sarcolemma
Molecular classification: Lipid bilayer, Membrane

Overview

The myocardial cell membrane, or sarcolemma, is the specialized plasma membrane that surrounds each cardiac muscle cell (cardiomyocyte). It plays a critical role in maintaining cellular integrity, facilitating electrical signaling, and regulating contraction in heart muscle tissue. It contains T-tubules, caveolae, ion channels, pumps and receptors. The sarcolemma interfaces with the extracellular matrix.

Other names: SarcolemmaCardiomyocyte membrane

Mechanism of action

N/A

Biological functions

Electrical conductionExcitation-contraction couplingIon homeostasisSignal transductionMaintaining resting membrane potential

Disease associations

Cardiovascular diseaseArrhythmiaHeart failureCardiomyopathy

Interacting drugs

Adrenaline

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