Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Myosin light chain 5 (MYL5)
- Target
- MYL5
- Molecular classification
- Other, myosin regulatory light chain, calcium-binding protein, structural muscle protein
01
Overview
Myosin light chain 5 (MYL5) is a phosphorylatable regulatory light chain of the hexameric ATPase cellular motor protein myosin. It is involved in the regulation of myosin function, important for muscle contraction and actin cytoskeleton-dependent processes. MYL5 localizes to mitotic spindle poles and is necessary for proper cell division, contributing to spindle assembly, chromosome congression, and segregation. It binds calcium and contains EF-hand domains, and is expressed in fetal muscle, adult retina, cerebellum, and basal ganglia. MYL5 variants have been implicated in Limb-Girdle Muscular Dystrophy and are being investigated as a possible prognostic marker in breast cancer
- Other names
- MYLC2MyLC-2Myosin regulatory light chain 5Superfast myosin regulatory light chain 2myosin, light chain 5, regulatorymyosin, light polypeptide 5, regulatorysuperfast myosin regulatory light chain 2
02
Biological functions
Regulation of muscle contractioncell division (mitosis)calcium ion bindingactin cytoskeleton remodeling
03
Disease associations
Limb-Girdle Muscular Dystrophypossible breast cancer prognosis
04
Biomarkers
possible prognostic marker in breast cancermuscle disease marker (Limb-Girdle Muscular Dystrophy risk)
Beyond the preview
Go deeper on Myosin light chain 5 (MYL5).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Myosin light chain 5 (MYL5).