Target intelligence / Profile preview

Myosin light chain kinase (chicken) (Gal d 7)

Target
Gal d 7
Molecular classification
Allergen, Avian protein, Muscle protein
01

Overview

Gal d 7 is the designation for a major allergen identified in chicken meat, corresponding to myosin light chain kinase or myosin light chain 1. It is recognized by IgE from individuals primarily sensitized to chicken meat and contributes significantly to poultry meat allergies. Recombinant Gal d 7 can serve as a diagnostic marker for true (primary) poultry meat allergy due to its high thermal and enzymatic stability and cross-reactivity with allergens from other poultry species. Notes: - “Gal d 7” is not a therapeutic target such as a receptor, enzyme, or transporter involved in human pharmacology—it is primarily a food allergen, specifically an avian muscle protein allergen, and does not meet the typical definition of a drug target or disease target in biomedical research. - The canonical name is best described by its protein function and source: "Myosin light chain kinase (chicken)" or simply “Chicken myosin light chain kinase.” - Its primary relevance is as a protein allergen used in the diagnosis of food allergies, not as a target for drug development or therapeutic intervention. - There are no known drugs that interact with this target, as it is not a target for pharmacological modulation. If you are seeking "therapeutic targets," Gal d 7 does not qualify under usual pharmaceutical or biological target definitions.

Other names
Gal d 7Chicken myosin light chain kinaseChicken allergen Gal d 7
02

Biological functions

Muscle contraction (as part of myosin system)Allergenicity
03

Disease associations

Food allergy (meat allergy, specifically poultry/chicken meat allergy)
04

Safety considerations

Major sensitizer in poultry meat allergy; highly stable and resistant to digestion, increasing allergenic potential
05

Biomarkers

Diagnostic marker for genuine poultry meat allergy

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