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Target intelligence / Profile preview
Myosin regulatory light chain 11 (MYL11)
- Target
- MYL11
- Molecular classification
- Structural protein (myosin light chain), EF-Hand protein superfamily
01
Overview
Myosin regulatory light chain 11 (MYL11) is a protein component of the myosin motor complex, specifically associated with fast skeletal muscle fibers in humans[1][3][8]. It binds calcium ions and acts as a structural constituent, enabling muscle contraction through the regulation of the actin-myosin interaction[3][4][8]. MYL11 plays a crucial role in maintaining muscle integrity during early development and is localized within muscle tissue, cytosol, and lysosomal membranes[1][7][8]. It belongs to the EF-hand protein superfamily and is encoded by the MYLPF gene located on chromosome 16 in humans[1][3]. There are no established roles as a therapeutic target, nor are there known interacting drugs, mechanisms of action, biomarker utility, or safety concerns reported in current literature.
- Other names
- Fast skeletal myosin light chain 2Myosin light chain 2BMRLC2MYLPFHUMMLC2BDA1CHSRLCMyosin light chain, phosphorylatable, fast skeletal muscleMyosin regulatory light chain 2, skeletal muscle isoform
02
Biological functions
Muscle contractionCalcium ion bindingStructural constituent of muscleMaintenance of muscle integrity during development
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