N-acetylaspartylglutamate synthase A (RIMKLA)

N-acetylaspartylglutamate synthase A (RIMKLA) is an enzyme predicted to catalyze the synthesis of the neuropeptide N-acetyl-L-aspartyl-L-glutamate (NAAG) and the related peptide N-acetyl-L-aspartyl-L-glutamyl-L-glutamate[2][5]. It is involved in amino acid metabolic processes, particularly those related to the glutamine family[2][4]. RIMKLA is a protein-coding gene expressed in various tissues, and its altered function has disease associations, including Canavan disease and leukodystrophy[2]. The protein is primarily localized in the cytoplasm and cytosol[2][4], with no evidence for direct interaction with approved drugs or formal biomarker or safety concern assignments as of available data.

Other names

Ribosomal modification protein rimK like family member AFAM80ANAAG synthetase ANAAGSMGC47816RP11-157D18.1NAAGS-IIN-acetylaspartylglutamylglutamate synthase ARibosomal protein S6 modification-like protein AN-acetylaspartylglutamate synthetase IIfamily with sequence similarity 80 member A