Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
N-myristoyltransferase 1 (NMT1)
- Target
- NMT1
- Molecular classification
- Enzyme, Transferase
01
Overview
N-myristoyltransferase 1 (NMT1) is an enzyme responsible for the covalent attachment of myristate to proteins, a process crucial for protein localization and function. It is involved in cell growth, development, and tumorigenesis, and is being investigated as a therapeutic target in cancer and parasitic infections.
- Other names
- Glycylpeptide N-tetradecanoyltransferase 1Myristoyl-CoA:protein N-myristoyltransferase 1
02
Mechanism of action
Myristoyltransferase inhibition
03
Biological functions
Protein-membrane interactionsSubcellular localizationProtein-protein interactionsConformational changes in target proteinsCell growth and development
04
Disease associations
CancerInfection
05
Safety considerations
Potential for off-target effects due to the broad substrate specificity of NMT1Development of resistance to NMT1 inhibitors
Beyond the preview
Go deeper on N-myristoyltransferase 1 (NMT1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on N-myristoyltransferase 1 (NMT1).