NACA pseudogene 10 (NACAP10)

NACA pseudogene 10 (NACAP10), also known as nascent polypeptide-associated complex alpha subunit 2 pseudogene, is annotated as a pseudogene in the human genome, mapped to chromosome 8 (chr8:67569416-67570078, hg38)[2][3]. Pseudogenes are genomic sequences related to protein-coding genes but do not encode functional proteins due to disabling mutations or lack of necessary regulatory elements[6]. NACAP10 is annotated in major genomic resources (e.g., NCBI Gene: 100132812, Ensembl: ENSG00000254253)[2][3], and is derived from or related to the parental gene NACA (nascent polypeptide-associated complex subunit alpha)[4]. There is no evidence for translated protein, disease associations, or utility as a therapeutic target, biomarker, or drug-interacting molecule. While some pseudogenes have been shown to regulate gene expression through non-coding RNA mechanisms in other gene families (e.g., through microRNA sponging or competitive endogenous RNA activity)[6], there is no such documented activity for NACAP10. Thus, NACAP10 is best classified as a noncoding genomic element with no known protein product or direct role in human health or disease[2][3][4].

Other names

nascent polypeptide-associated complex alpha subunit 2 pseudogene