NACA pseudogene 8 (NACAP8)

NACA pseudogene 8 (NACAP8) is a human pseudogene listed in genomic databases (e.g., NCBI Gene 101928685, Ensembl ENSG00000257210) and is also known as NACAP3. It is located on chromosome 12 (chr12:93124063-93124543, hg38). There are no known protein products, biological activities, disease associations, or roles as a therapeutic target. The gene is classified as a pseudogene due to its high sequence similarity to the nascent polypeptide-associated complex alpha polypeptide gene but is not believed to encode functional RNA or protein. No experimental studies, clinical uses, or therapeutic development are associated with NACAP8. Importantly, published literature describing pseudogene 8 with clear roles in cancer (as a biomarker or lncRNA therapeutic target) refers to DUXAP8—a totally different gene—rather than NACA pseudogene 8. There is thus a risk of significant misattribution if these two are conflated. Functional and disease information found in cancer and lncRNA literature (DUXAP8) does not apply to NACA pseudogene 8 (NACAP8) but to Double homeobox A pseudogene 8 (DUXAP8), which is distinct and located on a different chromosome. NACA pseudogene 8 is a non-protein-coding genomic sequence with no known clinical or biological significance at this time. If further molecular or therapeutic information is needed about "pseudogene 8" in the context of lncRNAs and cancer, consult the entry for DUXAP8 (“Double homeobox A pseudogene 8”), not NACAP8.

Other names

NACAP3NACA pseudogene 3nascent polypeptide associated complex alpha subunit pseudogene 3nascent-polypeptide-associated complex alpha polypeptide pseudogene 3