NADH:ubiquinone oxidoreductase core subunit V2 pseudogene 1 (NDUFV2P1)

NDUFV2P1 is a non-transcribed pseudogene related to the NADH:ubiquinone oxidoreductase core subunit V2 encoded by the functional gene NDUFV2. While NDUFV2 is a core component of mitochondrial complex I and involved in electron transport and oxidative phosphorylation[1][2][5], NDUFV2P1 itself does not encode a functional protein and has no known biological role. This pseudogene is found on chromosome 19, distinct from the location of the functional gene on chromosome 18[1][2]. Pseudogenes like NDUFV2P1 may occasionally regulate their parent gene's expression at the RNA level, but no direct regulatory or pathological role is established for NDUFV2P1[2]. In summary: NDUFV2P1 is not a gene of therapeutic or diagnostic interest and has no biological function, disease association, or drug interactions. It should not be confused with the functional NDUFV2 gene, which encodes a mitochondrial enzyme subunit with major bioenergetic and clinical significance[1][2][5].

Other names

NADH dehydrogenase (ubiquinone) flavoprotein 2 pseudogene 1NDUFV2 pseudogene 1