NALF1 intronic transcript 1 (NALF1-IT1)

NALF1 intronic transcript 1 (NALF1-IT1) is a human long non-coding RNA (lncRNA) transcribed from an intronic region of the NALF1 gene. It is officially recognized in gene databases (HGNC:41503, NCBI Gene:100874375, Ensembl:ENSG00000227248) and is also known as FAM155A-IT1. NALF1-IT1 is classified as an lncRNA, meaning it does not code for protein but may have regulatory roles in gene expression, chromatin state, or RNA metabolism, although specific biological functions are not well-characterized in the current literature[3][5][7]. Disease association has been reported with myoclonic juvenile epilepsy, but causal or mechanistic details are lacking[3]. NALF1-IT1 is not considered a therapeutic target such as a receptor or enzyme and does not have known drug interactions, mechanisms of action, biomarker applications, or safety issues. Note: If your focus is on a molecule relevant for therapeutic targeting (such as for drug discovery), NALF1-IT1 is not appropriate, as it is a non-coding RNA transcript rather than a functional protein target. Confusion could arise between NALF1-IT1 and the protein-coding NALF1 (NALCN channel auxiliary factor 1), which *is* implicated in neuronal excitability and pain pathways[1][2]. If you need details about the protein-coding gene, please clarify; otherwise, the above information most accurately reflects the NALF1-IT1 lncRNA.

Other names

FAM155A-IT1