Nanog homeobox pseudogene 9 (NANOGP9)

Nanog homeobox pseudogene 9 (NANOGP9) is classified as a **pseudogene** within the NANOG homeobox gene family. Pseudogenes are segments of DNA that resemble functional genes but are generally considered nonfunctional due to mutations that prevent them from encoding active proteins[2][8][9]. NANOGP9, located on the X chromosome at Xq12, is one of several NANOG-related pseudogenes in the human genome[2]. Unlike the functional NANOG gene—which encodes a homeobox transcription factor critical for the maintenance of pluripotency in embryonic stem cells—NANOGP9 does **not** produce a functional protein and does not play a direct role in biological processes, disease, or drug interactions[2][8][9]. Notes on correctness: - NANOGP9 is not a direct therapeutic target, nor does it encode an active transcription factor[8][9][2]. - While some NANOG pseudogenes (e.g., NANOGP8) may be transcribed and have rare roles in cancer biology, there is no evidence to support a functional or pathological role for NANOGP9[9]. - Pseudogenes may, in rare circumstances, be co-opted for regulatory or other functions, but no such data exist for NANOGP9. Summary: NANOGP9 is a noncoding pseudogene, not a functional molecular target or a gene of current therapeutic, diagnostic, or biomarker interest[2][8][9].

Other names

NANOGP6