Nasal mucosa inflammation mediators

"Nasal mucosa inflammation mediators" refers to a broad and heterogeneous collection of signaling molecules released in the nasal lining during the development and resolution of inflammation. These include cytokines (e.g., interleukin-4, interleukin-5, interleukin-13, tumor necrosis factor alpha), chemokines (e.g., eotaxin), eicosanoids (e.g., prostaglandins, leukotrienes), histamine, and specialized pro-resolving mediators (e.g., resolvins, protectins, maresins). These mediators are produced and released by immune cells (mast cells, eosinophils, neutrophils, T-cells), epithelial cells, and vascular endothelium in response to allergens, pathogens, and irritants. They orchestrate the immune response, vascular permeability, mucus secretion, cell recruitment, and, ultimately, symptom generation in conditions such as allergic rhinitis and chronic rhinosinusitis[1][2][3][4][7]. Key notes: - This is *not* a canonical molecule, receptor, enzyme, or single molecular target, but a functional grouping used to describe the mediators present in nasal mucosal inflammation. - For structured data, you will need to specify individual targets (e.g., "Interleukin-5", "Histamine receptor H1", "Eotaxin", etc.) depending on your application[1][3][4][7].

Other names

Pro-inflammatory nasal mediatorsNasal inflammatory mediatorsInflammatory mediators in nasal mucosa