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Natural cytotoxicity triggering receptor 2 pseudogene

Molecular classification
Other
01

Overview

Natural cytotoxicity triggering receptor 2 pseudogene (ENSG00000274256) is a non-protein-coding genomic locus annotated as a pseudogene related to the NCR2 gene, which encodes the functional NKp44 receptor. Unlike the functional NCR2, this pseudogene does not produce an active receptor protein and is therefore not involved in NK cell function, immune recognition, signaling, or any established therapeutic role[7]. Misidentification with the functional NCR2 gene could result in scientific error; the correct drug target and receptor function information pertains to NCR2 (Ensembl ENSG00000096264)[2][7]. If your intent was the immune receptor itself, you should refer to the protein-coding NCR2, not this pseudogene.

Other names
NCR2 pseudogenenatural cytotoxicity triggering receptor 2 pseudogene

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