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NCAM1 antisense RNA 1 (NCAM1-AS1)
- Target
- NCAM1-AS1
- Molecular classification
- Long non-coding RNA (lncRNA), Antisense RNA, Non-coding RNA, Other
01
Overview
**NCAM1 antisense RNA 1** (NCAM1-AS1) is a long non-coding RNA (lncRNA) gene located on chromosome 11, situated within the intronic region of the NCAM1 gene[1]. It does not encode a protein but is believed to play a regulatory role in controlling the expression of NCAM1, a key cell adhesion molecule essential for neuronal development, differentiation, cell migration, and possibly other cellular processes[1][2]. NCAM1-AS1 has been found to be expressed in multiple tissues at various developmental stages, particularly in brain and other neural tissues, and is hypothesized to regulate NCAM1 function through antisense-mediated mechanisms[2]. While alterations in its expression or function may impact diseases such as cancer or neurological conditions, NCAM1-AS1 itself is not currently considered a direct therapeutic target, and specific drugs or biomarkers related to its action have not yet been established[1][2][8].
- Other names
- NCAM1-AS1NCAM1 antisense non-coding RNANCAM1-ASnatural antisense RNA to NCAM1
02
Biological functions
Regulation of gene expressionRegulation of neural cell adhesion molecule 1 (NCAM1) expressionCell proliferationCell differentiationCell migration
03
Disease associations
CancerPotential roles in neurological disorders (exact disease associations still under study)
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