Target intelligence / Profile preview

NCF4 antisense RNA 1 (NCF4-AS1)

Target: NCF4-AS1
Molecular classification: Long noncoding RNA (lncRNA), Antisense RNA, Noncoding RNA, Natural antisense transcript (NAT)

Overview

NCF4 antisense RNA 1 (NCF4-AS1) is a long noncoding (non-protein coding) RNA molecule, annotated in the human genome adjacent to and transcribed antisense to the protein-coding NCF4 gene[4][6]. It is classified as a natural antisense transcript (NAT). As with other antisense lncRNAs, NCF4-AS1 may regulate its corresponding sense gene via transcriptional interference, alteration of mRNA stability, or epigenetic modifications, though its precise physiological or disease roles remain uncharacterized in current scientific literature[7]. There is no evidence at present that NCF4-AS1 functions as a direct receptor, enzyme, transporter, or similar classical drug target, nor is it implicated as a clinical biomarker or pathology-relevant locus in humans[4][6]. If you require information at the sense gene/protein level (NCF4: Neutrophil cytosolic factor 4), this is a different entity and is a bona fide therapeutic target in some immune and inflammatory conditions, but NCF4-AS1 remains only an annotated lncRNA without direct drug, clinical, or disease evidence at this time[4][6].

Other names: CTA-833B7.2NCF4-AS1

Biological functions

Likely regulates gene expression of the sense NCF4 gene at the RNA level (inferred from general NAT/lncRNA biology)Could influence transcriptional or post-transcriptional processes such as mRNA stability, methylation, chromatin configuration, or translation (based on lncRNA and antisense RNA mechanisms)Other (insufficient direct evidence for more specific functions)

Disease associations

Other (no direct evidence for roles in cancer, inflammation, neurodegeneration, cardiovascular disease, or infection for NCF4-AS1 itself)

Beyond the preview

Go deeper on NCF4 antisense RNA 1 (NCF4-AS1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on NCF4 antisense RNA 1 (NCF4-AS1).

Explore the full profile