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Target intelligence / Profile preview
Nck-associated protein 5 (NCKAP5)
- Target
- NCKAP5
- Molecular classification
- Other (cytoskeletal-associated adapter protein)
01
Overview
Nck-associated protein 5 (NCKAP5) is a cytoplasmic protein that interacts with the SH3-containing adaptor protein Nck and is implicated in the regulation of microtubule dynamics, including microtubule bundle formation and depolymerization. It is predicted to be active at microtubule plus-ends and is expressed in a wide range of human tissues, including brain and peripheral organs. NCKAP5 is not currently recognized as a therapeutic target, and no drugs are known to specifically modulate its function.
- Other names
- ERIH1ERIH2NAP5NAP-5Peripheral clock protein 2ERIHperipheral clock protein
02
Biological functions
Microtubule bundle formationMicrotubule depolymerizationCytoskeletal organization
03
Disease associations
Other (no direct link to major disease categories as of current data)
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