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NCOR1 pseudogene 3 (NCOR1P3) is a non-coding segment of DNA on chromosome 17 or 20 that closely resembles the protein-coding NCOR1 gene but does not code for a functional protein. Pseudogenes like NCOR1P3 arise from duplication or retrotransposition events and typically lack regulatory sequences or contain mutations that disable their ability to produce functional proteins. There is no known biological or therapeutic significance for NCOR1P3 itself; all known functions and disease associations belong to the functional gene nuclear receptor corepressor 1 (NCOR1)[1][4]. Key distinction: - Information on NCOR1P3 is very limited, and all characterization refers to its status as a pseudogene of NCOR1, not as an active molecular target. The canonical, functional target would be *Nuclear receptor corepressor 1 (NCOR1)*, not NCOR1P3. If you meant to research a functional target, you likely want "Nuclear receptor corepressor 1 (NCOR1)"[1][2][3][4][5]. Summary: NCOR1P3 is a pseudogene and is not a therapeutic target. There is no evidence for biological, therapeutic, or diagnostic relevance for NCOR1P3, and its mention should be flagged as incorrect when searching for druggable targets. All noted biological roles and pathways relate instead to its parent gene NCOR1.
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