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NDNF antisense RNA 1 (NDNF-AS1) is a long non-coding RNA gene transcribed from the antisense strand of the NDNF locus. It belongs to the class of natural antisense transcripts (NATs) and is affiliated with lncRNAs, which are defined as transcripts longer than 200 nucleotides that regulate gene expression by various mechanisms, such as altering mRNA stability, splicing, or translation. The precise biological roles and mechanisms of NDNF-AS1 remain unclear, and there is currently no evidence demonstrating its involvement as a therapeutic target, validated biomarker, or disease-associated molecule. Its molecular identity is well-established, and there are no major aliases outside its canonical gene name and abbreviation. NDNF-AS1 is listed in major genetic databases and conforms to current standards in lncRNA classification.
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