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NDNF antisense RNA 1 (NDNF-AS1)

Target
NDNF-AS1
Molecular classification
Long non-coding RNA (lncRNA), Natural antisense transcript (NAT), Non-coding RNA
01

Overview

NDNF antisense RNA 1 (NDNF-AS1) is a long non-coding RNA gene transcribed from the antisense strand of the NDNF locus. It belongs to the class of natural antisense transcripts (NATs) and is affiliated with lncRNAs, which are defined as transcripts longer than 200 nucleotides that regulate gene expression by various mechanisms, such as altering mRNA stability, splicing, or translation. The precise biological roles and mechanisms of NDNF-AS1 remain unclear, and there is currently no evidence demonstrating its involvement as a therapeutic target, validated biomarker, or disease-associated molecule. Its molecular identity is well-established, and there are no major aliases outside its canonical gene name and abbreviation. NDNF-AS1 is listed in major genetic databases and conforms to current standards in lncRNA classification.

Other names
NDNF-AS1NDNF antisense RNA 1GC04P121074GC04P121127GC04P121247GC04P121414GC04P121625GC04P121847GC04P122073GC04P122288
02

Biological functions

Likely regulates gene expression of NDNF through antisense mechanisms, including influencing mRNA stability, splicing, and translationMay participate in epigenetic regulation and cis/trans modulation
03

Disease associations

No established association with specific diseases such as cancer, neurodegenerative disorders, or cardiovascular diseases

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