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NDST1 antisense RNA 1 (NDST1-AS1) is a long non-coding RNA transcribed from the locus opposite the NDST1 gene. It does not encode a protein and is presumed to function in regulation of NDST1 gene expression via antisense or epigenetic mechanisms. There is currently no strong evidence supporting roles in specific diseases, no drugs targeting NDST1-AS1, and no known biomarker utility or safety concerns. NDST1-AS1 is distinct from NDST1, which encodes an essential bifunctional enzyme involved in heparan sulfate biosynthesis.
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