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Target intelligence / Profile preview
Neisseria meningitidis capsular polysaccharide A (Serogroup A CPS)
- Target
- Serogroup A CPS
- Molecular classification
- Polysaccharide, Capsular Polysaccharide
01
Overview
Neisseria meningitidis capsular polysaccharide A is the primary surface carbohydrate antigen of N. meningitidis serogroup A, a major cause of epidemic bacterial meningitis worldwide. The capsule is a key virulence factor, enabling the bacterium to evade host immune responses and survive in the bloodstream by resisting complement-mediated killing and phagocytosis.
- Other names
- Group A capsulesacA-D / mynA-D / csaA-D
02
Mechanism of action
Antibody-mediated neutralization and complement activation
03
Biological functions
Immune evasionVirulence factorAntigen presentation
04
Disease associations
InfectionMeningitis
05
Interacting drugs
Polysaccharide-protein conjugate vaccines
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